The following article talks about the various side effects and treatment options available to osteoporosis patients.
What are the medications that are being given to millions of men and women globally to deal with osteoporosis? Mainly, there are 3: alendronate, Boniva® and Actonel®. There are additional ones that are given intravenously but this article will focus on the three most common.
Certain osteoporosis medicines are categorized as bisphosphonates, which is an component being utilized for several years in plant food, soaps, dishwashing detergents and heavy-duty lubricating substance. Alendronate, the most popular of the three bisphosphonates, is Merck’s second best selling medicine. It has exceeded four billion in gross sales and millions of orders are scripted annually.
Furthermore, Merck has already reserved an enormous amount of money for a defense monetary fund for cases associated with the side effects that, for several individuals, are extremely debilitating.
Actonel® is the second most booming medicine in this class and coincidentally, Proctor and Gamble, who produces Actonel, also manufactures laundry detergent and toothpaste. Boniva® is a given once a month.
The bisphosphonates in the medications work by lessening the pace at which a person’s bones decrease their density. The bones collapse and then construct back up, in their normal rhythm of development. When people are younger their bones develop more rapidly than they crumble, and of course as people age this system slackens.
The most frequent side effects of the bisphosphonates include gastrointestinal issues. They include responses like:
- Redness of the esophagus
- Ulcer of the esophagus
- Trouble swallowing (dysphagia)
The list carries on with a host of additional signs that include dental issues, blood coagulation issues, fretfulness, anemia, joint issues, muscle infliction, and vision decline. These harmful side effects are permanent and can be associated with osteonecrosis, which is the death of bone due to inadequate blood supply.
This disease is extremely painful and may produce ulcerations, infection, open bone and sores.
The trouble with all the side effects is that additional medicines are then given to treat them. People begin using an acid reducing agent to treat the gastrointestinal issues, an anti-inflammatory to treat the inflammation issues, and a pain reducer to care for the joint and muscle issues.
Is this actually the best way to care for a disease which until a view years ago was not even categorized as a disease? The Mayo Clinic declared that thirty-seven percent of females older than fifty don’t meet the real criteria of osteoporosis and are somehow mistakenly diagnosed.
That seems to vanish very quickly. After ordering pencils, pencils, pencils, and more pencils, there is nothing left for all of the projects that the students enjoy so much. And, after ordering some paper and glue stick for 125 students over ten months, there will probably not be anything left for high-interest technological gadgets. Unless the teacher is willing to have a daily struggle over students bringing a pencil to class, meaning the pencils will be taking up much of the budget, there is going to have to some creativity, sharing, and give and take involved in the ordering process.
Most teachers have about $250.00-$500.00 to spend on supplies for the next school year. This figure does not include books or computers, but it does include items like bulletin board decorations (which no longer seem to be reusable, since over the course of the year students feel they can write on them and rip them down when the teacher is absent), paper, pens, colored pencils, poster board, videos or DVDs, machines on which to present the videos or DVDs, overhead transparencies, markers (dry erase, overhead, and washable), erasers, chalk, portfolio folders, file folders, printer toner. $500.00 may look like a lot of money at first, but ten boxes of 144 pencils costs approximately $120.00. If a teacher in middle school sees 125 students a week, and 50 pencils are “borrowed” a week, then in around 30 weeks, there will be no more pencils, and that is figuring low, because the student is not going to bring that pencil to class all week.
The average teacher puts about $500 of his/her own money into the classroom per year; that is according to a 2002 report. That is a personal choice, by a dedicated teacher who wants to add a little extra to whatever is going on in the classroom, whether it is for 挂ssr加速软件, supplies, or trip fare, whatever. Some teachers bring supplies that are at home to the classroom, such as older televisions, educational games their own kids have outgrown, and other items, such as computer disks or software, electric fans in places where none are supplied. Some teachers will not spend a dime in the classroom or bring anything in either. This is also a choice.
Teachers need to look into sharing with each other. Perhaps if four teachers each have $25.00 left over, that is $100.00, enough for a Math Safari that can be shared (and devise a schedule for students to use it). Share televisions and DVD players. Bring the antiquated digital camera from home to liven up lessons. Also, look into what DVD’s are available at the public library and determine which teachers are teaching the same topic at that time. Arrange for a mass showing of the DVD. That is another $20.00 saved! Have students work in groups, rather than individually, to save on art supplies, and also work in conjunction with the art teacher so skills can be incorporated or not repeated.
Teachers tend to work in isolation and this should not be. This year, when ordering, collaborate. Someone may lend you the $1400.00 digital microscope you need for just one class period.
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Associate your brand with an online domain
Don’t lose yourself in details. The name of the website has to be brief, to say exactly what it is about, and easy to remember.
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Just think of Facebook and DropBox. Those names can’t be easily forgotten, and they are also clear what the website is about.
A small number of characters
www.my-small-car-repair-shop–in-chicago.com might look like a complete domain name telling a lot about your business, but do you think anyone would remember it? As shorter, as better, and even if you have a lot to say about your business, say it in the pages of the site. The domain name has to be short, and it has the goal to attract the click. Once you got it, the content becomes essential, but not before that. You can still find combinations and proper free domain names in .com, but you can also go for the more specific terminations. Car-repair.chicago is a lot better, and people will remember it easily.
Easy to pronounce
If someone wants to find a second-hand item fast, he will go on as it is easy to pronounce and remember. Word of mouth is still the best marketing tool, but no one will remember www.my-small-car-repair-shop–in-chicago.com. You want your users to recognize and promote your name, and this can only be done with a short and relevant domain name.
Avoid numbers and symbols
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Try to think about your audience as well. If you plan to promote your website mostly on Google, the domain name still counts, but a lot less than if you would choose another marketing platform. Google will rank your website based on its content, even if it has an impossible name. But on social media, people have to remember and talk about your site, and a complicated name will make this impossible.
A company should give you a domain checker to look for the best name, packages for shared and , and also the customer support required by beginners, all of these at some reasonable prices that your business affords. …
There are hundreds of different products commonly used as promotional gifts from mugs to baseball hats or mousemats to calendars. Personalized pens or pencils are one of the most cost effective items to consider for business marketing as they can be purchased for as little as 8 cents when bought in bulk.
Printed pens are available to buy online at a variety of price points and most styles of pen can be customized, in multiple colors if necessary, with specific company logos, website details and telephone number, a sure way to remind customers who to call first.
Promotional Printed Pens
While cheap printed pens are attractive from a cost angle, it’s important to remember that cheap can often look nasty; the pen may be too thin for large hands or it may leak due to poor quality refills leaving a poor but lasting impression. It may therefore be better to spend a few extra cents on a better quality pen which feels good to use and, being bigger and wider, will allow more space for a larger logo or additional company information.
Types of Personalized Pens
Imprinted pens fall into the following broad categories:
- Ballpoint pens – available in twist, click and stick form, they are usually the cheapest and offer the widest range of style choice in multiple colors. Refills usually last the longest so pens have a longer marketing life.
- Rollerballs – offer better, smoother writing quality but are more expensive often as they come with a cap.
- Gel pens – refills do not have longevity but they are excellent writing instruments and will make a lasting impression.
- Fine liners and fibretips – these are not as popular as printing is more expensive on their metal outers.
- 挂ssr加速软件 – expensive but a good option for executive corporate gifts. They can also be used as part of a personalized boxed gift set with a matching ballpoint pen and pencil.
Simple wooden pencils are a cost effective and eco-friendly alternative to plastic pens.
Alternative Promotional Gifts
Markers, highlighters and sticky notes may not be considered by many promotional product buyers but offer a good alternative to pens and pencils, especially as costs are now far lower due to their popularity. Highlighters and sticky notes also offer a greater surface area to place promotional messages or memorable logos.
Cost of Promotional Pens and Pencils
Small wooden pencils start from around 8 cents when bought in bulk quantities of 5000+ from online stores like PENSRUS; full size pencils cost upwards of 11 cents each. Cheap stick pens start at 16 cents per piece; better quality ball points like the Springster (see picture below) cost from 43 cents dependent on quantity; expect to pay from $1.34 per piece for branded products like a good quality Paper Mate® ballpoint pen.
Pen and pencil gift sets cost upwards of $7.50 with boxed executive pen sets costing upwards of $25. It is best to compare quality and price of options on offer from several different websites before placing an order.
Promotional pens can be a great marketing tool as well as being practical gifts for corporate clients. Simply use them as cheap giveaways at stores and trade fairs or invest in higher quality items for personalized gifts.
A look at director Nicolas Winding Refn’s sequels to his cult hit ‘Pusher.’
Having found himself in debt after directing 挂ssr加速软件(2003) Nicolas Winding Refn made two back-to-back sequels to his breakthrough movie 挂ssr加速软件(1996) to get out of financial trouble. Refn felt Fear X was his “best and most ambitious film” to date and was wounded by its perceived failure. The documentary Gambler (Phie Ambo 2006) covers Refn’s struggle with bankruptcy and how making more 挂ssr加速软件movies was the only real choice for Refn. The original ended with Frank’s (Kim Bodnia) fate unresolved as he found himself out of cash and being hunted down by Serbian drug dealer Milo (Zlatko Bulic) and his associates. Pusher II: With Blood on My Hands focuses on Frank’s former friend Tonny (Mads Mikkelsen) as he tries to get his life back on track after spending time in prison.
Pusher II: With Blood on my Hands
Hapless skinhead Tonny might have RESPECT tattooed on the back of his head, but nobody respects him, especially not Smeden (Leif Sylvester), his estranged father who regards Tonny as a clown and wants nothing much to do with him. Smeden owns a garage and operates a car thief ring so Tonny steals a Ferrari to impress his father, but is too daft to realise the opportunistic theft of such an expensive item attracts too much heat.
Tonny then teams up with the equally hopeless Kurt ‘the Cunt’ to conduct the worst, and quite possibly the funniest drug deal in history. Unfortunately this transaction is with Milo, who may see the funny side of Kurt flushing his stash down the toilet, but still demands to be paid. There is a vague hint at Frank’s fate with Milo asking Tonny if he’s seen his old friend around recently suggesting he may have escaped Copenhagen. Tonny is also having trouble with his ex, the mother of his child who hates him for impregnating her and treats their child as a burden.
Winding Refn likes to put his characters in situations where they are cornered and finding a way out seems impossible. Using the same low-key gritty style as the original, Refn mixes social realism with moments of transcendence. Though unremittingly bleak, Pusher II: With Blood on My Hands is also very funny. Mikkelsen is able to make Tonny sympathetic despite his criminal tendencies and the various humiliations heaped upon him. It all leads to a tender, moving finale with Tonny finally gaining a measure of respect and perhaps a new start.
Pusher III: I Am the Angel of Death
With the success of Pusher II assured Winding Refn was able to make another sequel, this time focusing on Milo as he deals with drug addiction, Albanian gangsters, and his daughter’s birthday party. Milo gets a shipment of ecstasy instead of heroin and reluctantly agrees to sell it. There is a new generation of dealers on Copenhagen’s streets and Milo is a little out of his time. He has no idea how to deal ecstasy, or even that what he is trying to sell is actually confectionary. Now in debt to the Albanians Milo has to work for them and finds himself under the kind of pressure he’s used to putting other people under.
Though not as good as the earlier films Pusher III: I Am the Angel of Death still holds the attention. Much of this is down to Zlatko Bulic’s performance. Milo is no longer as fearsome and must turn to his enforcer Radavan (Slavko Labovi?) from the first film. In 挂ssr加速软件Radavan was the kind of guy who would tear your kneecaps off, but there is a remarkable scene where this terrifying enforcer sweetly explains to Frank how he dreams of opening his own restaurant. Now older and bespectacled, Radavan has realised his dream of being a restaurateur and he is wary of returning to his former life.
Both sequels did well enough at the Danish box-office and through international sales to get Winding Refn back in the black. After a brief detour into British television directing an episode of ITV’s Miss Marple series Winding Refn made Bronson (2008) and reunited with Mads Mikkelsen starring Viking movie Valhalla Rising (2009). 挂ssr加速软件has inspired a couple of British remakes; a low-budget version set in Leicester amongst the Hindi community directed by Assad Raja, and a forthcoming film by Luis Prieto starring Richard Coyle as Frank. Zlatko Bulic will apparently be reprising his role as Milo for the latter.
The rude revelation that referee Tim Donaghy may have tinkered with the outcome of games will add to a long list of conspiracy theories that the NBA is not entirely on the level. It shouldn’t.
While Donaghy’s alleged actions were unconscionable and could leave a permanent black eye on the league, they are nickel-and-dime stuff compared to the 1985 lottery drawing and a handful of postseason games that have historically raised the eyebrows of even the most ardent NBA fans.
Donaghy may have lined the pockets of gamblers with tens of thousands of dollars; those other incidents would have had a financial impact of millions and perhaps billions.
In fact, a friend who worked at the NBA at the time believed that Game Six of the 2002 Western Conference finals – the one where the Lakers shot a million free throws in the fourth quarter and Kobe Bryant got away with a suspension-worthy shot to the face of a member of the Sacramento Kings – was fixed.
His reasoning was that the league’s TV contracts were up for renewal that summer and that the NBA could not afford to have the Kings and the New Jersey Nets – a pair of unknowns to the casual fan base which drives viewership – establishing the ratings for the Finals, which would be used as the negotiating point for the networks interested in televising the league.
The numbers make it hard to argue with his thought process. Lakers-76ers in 2001, a series that featured two big markets, Shaquille O’Neal, Kobe Bryant and lightning-rod MVP Allen Iverson, had an overall 12.1 rating. Spurs-Nets in 2003, which had no large markets or larger-than-life personalities, did just a 6.5, the lowest-rated Finals before this year.
It’s easy to imagine the NBA wanting the Lakers and the second-largest market in the Finals. But it’s almost unfathomable to imagine the league fixing Game Six, then leaving Game Seven – scheduled for Arco Arena, the toughest home court in the league – in the hands of the Lakers.
Kings-Lakers is one of a number of games that have come under scrutiny. Game Seven of the 1993 Western Conference finals between the Seattle SuperSonics and Phoenix Suns, Game Four of the 1997 Eastern Conference finals between the New York Knicks and Miami Heat and Game Seven of the 2001 Eastern Conference finals between the Milwaukee Bucks and Philadelphia 76ers are all on the list.
But those contests have three distinct differences between anything Donaghy may have been involved in. For one, at the root of any conspiracy theorist’s reasoning is that the league itself – not a “rogue individual,” as Donaghy was called by NBA commissioner David Stern – was behind the machinations.
If the NBA wanted to ensure a playoff game’s outcome – not the point spread, not the over/under, but the outcome – one referee or player would not be enough. It would need to have multiple members of a team of players or referees in the mix.
Secondly, there is no proof that Donaghy tinkered with playoff games, which are watched by a much larger national audience than regular-season games. A Hornets-Bobcats game in January, viewed only in the local markets and by hoops junkies on League Pass, would be much easier to manipulate.
And finally, what a handful of bettors with inside information could collect on an NBA game is chicken feed compared to the financial windfalls of advertising revenue from TV contracts. The eight-year extension signed last month with broadcast partners Disney and Turner is for $7.44 billion.
If you want to excoriate Donaghy for destroying the most sacred element of the NBA, go right ahead. But don’t include him in your conspiracy theory arguments. His alleged influence is not on that scale.
Fibroids are benign muscle tumors. They are the most common gynecological pathology. They are treatable, although it is not always necessary.
Fibroids are diagnosed in 20 to 25% of women over the age of 30. They are generally non-cancerous muscle tumors of the uterus that may or may not produce signs and symptoms. Malignancy may occur in .2 to 1% of cases. Some women have small fibroids while others may develop fibroids that are as big as grapefruit. Pregnancy often causes fibroids to grow, a process that may be reversed after childbirth.
Types of Fibroids
Fibroids, also called leiomyomas, are classified into one of three categories, although a fibroid may become large enough to be classified in two or all of these categories.
Submucosal fibroids growth within the endometrial cavity, which is the inner cavity of the uterus, or impinge on the endometrium, the inner lining of the uterus that is shed during menstruation.
Intramural fibroids grow in the muscular, middle layer of the uterus. They do not touch the endometrium or the outer layer of the uterus.
Subserosal fibroids occur in the outer, or subserosal layer of the uterus. They can cause bumps on the surface of the uterus or become pedunculated, becoming a growth that hangs off of the outside of the uterus.
Signs and Symptoms
When fibroids become large enough, any type of fibroid can cause pelvic pressure, pain, cramping, or urinary urgency and frequency. Submucosal fibroids can cause irregular bleeding ranging from mild spotting between periods to continuous, heavy bleeding. Fibroids growing on the backside of the uterus may cause back pain. Uterine position can affect symptoms as well. Women with uteruses that tip towards the back may experience back pain more so than women with uteruses that tip forward.
Diagnosis and Treatment
Pelvic ultrasound is used to diagnose fibroids. Due to the varying degree of size and density among fibroids, abdominal and transvaginal ultrasound are used. The size, location, and fibroid classification is determined. If fibroids are too dense for adequate ultrasound analysis, magnetic resonance imaging (MRI) may be used for further diagnosis.
Fibroids that do not cause significant problems are often closely watched with subsequent ultrasounds. Symptomatic fibroids may be surgically removed from the uterus, a procedure called a myomectomy. Hysterectomy, or removal of the uterus, may be another option when the uterus is mostly fibrotic. Uterine artery embolization (UAE) is a process in which the arteries supplying the fibroids with blood are blocked, causing the fibroids to shrink.
I work too much, too hard and too many hours. It is a responsibility thing. I have always had an overdeveloped sense of responsibility. I have never considered it to be a virtue, but I never looked at it as a fault either. I guess I just never thought much about it at all. The last six months have been hard around here. A bitter, unexpected divorce threw us into a emotional and financial maelstrom. I responded by working more and more. The kids have been wonderful. They have never complained or been difficult. They have stayed close to me to be available for the few cuddles and strokes I could find time for. Always trying to comfort and help as best they could.
It all exploded on me Christmas Day. Far too many hours and far too much physical effort took its toll. The exhaustion opened the way for double pneumonia to set in. I could not even sit up. I do not remember much about that first couple of days. I remember not being able to breathe and the pain…..but mostly I remember my babies. I remember them cuddling close to me and touching my face with their paws, I remember their soft encouragement in my ear as I lay struggling to breathe. The one memory I will never be able to forget is the abject terror on their faces when I was taken to the hospital.
I spent six days in the hospital. During that time, my babies did not eat or play or hardly even attend to bodily functions…they waited. Period, they just waited. My daughter was getting as worried about the kids as she was about me. No amount of consoling worked. On the 4th day I was able to talk to them on the telephone. They still would not eat, but at least they seemed a little less devastated. The other memory that I will never forget is the pure, unadulterated joy when I walked through the door, home at last. Both babies screamed in joy and threw themselves onto me. They will barley leave my side at all. They are permanently attached, and that is fine with me.
I learned a valuable lesson in this, nothing, and I mean nothing, is more important than the ones you love. I don’t know yet what I am going to do to keep us in “treaties” since my doctor says I cannot go back to my job, things my really get bad financially, but what ever happens, I know now that the important thing is that I love and I am loved. No amount of material possessions in the world will ever mean as much as the love and need I see in my babies faces every time I look at them. We may be short on “treaties” but we will be long on and time spent together.…
Baby showers are for showing new parents that there’s a circle of people that cares about them and the new life they are bringing into the world. Whether it is an intimate gathering or an elaborate affair make sure that there is lots of caring and fun going around.
There are no rules in organizing a baby shower. In making decisions about a baby shower keep in mind that the parents-to-be should feel loved and cared for at their shower.
Who Should Host the Baby Shower?
Any person could host a baby shower for someone close to them. It might be a good idea to consult the parents-to-be about what they would like. Do they want it to be a surprise? Who would they like to invite? In some instances it might be better to have two baby showers for the same couple.
What Will We Do at the Stork Tea?
Choose a theme for the shower based on the preferences of the parents-to-be. The host of the baby shower should know them well or work closely with someone who does. Not everyone is comfortable with guessing- or group games and might rather prefer a subdued atmosphere with classical music and informal chatting.
One option is to structure the decorations such as flowers, table cloths and gift wrap around whether the couple is expecting a boy or a girl. Choose white lace and anglais for a girl and go for earthy colors and rough textures for a boy. If the gender of the baby is unknown, choose a color like orange or green.
Plan the menu accordingly – dainty petit fours for a girl and an earthy homemade soup or quiche for a boy. The aim is to create an ambiance in which the parents-to-be and guests will feel at home.
Should the Baby Shower be a Surprise or Not?
It is not always easy to keep a surprise from a new mom who will put Sherlock Holmes to shame with her snooping. Take the cue from her, if she would rather know, let her. Keep in mind that pregnancy hormones plus surprise parties may equal volatile emotions. While a bit of crying may be expected at a baby shower, one doesn’t want to cause an eruption of sadness or anger at her partner who lied to keep the secret.
Suitable Gifts for a Stork Tea
Gift registries, nappies-only, 3 – 6 months size only, no newborn size, consumable baby products only, cash only, gifts for mom only – the possible list of ways to request particular gifts is inexhaustible. Let the prospective parents decide how they would like to structure the gift giving, then make sure that you communicate it clearly to the guests.
Whatever limitations the invitation may place on gift giving, make sure the gift are thoughtful and personal. A handwritten card with a classic quote on parenting presented with a beautifully wrapped gift will certainly fulfill any requirements. For women who are expecting their second or third child, a gift for mom with a ‘baby sitting voucher’ attached may be the best choice. Steer clear from bath products for expecting moms for the risk of infection.
When Should we Have the Baby Shower?
Traditionally baby showers are held in the last trimester of pregnancy. A current trend is to have the baby shower after the baby is born. The advantages of having if after the arrival of the baby is that the gender of the baby would be known (in the case of parents who chose not to know before hand) and that all close friends and relatives will have an opportunity to see the new baby at one time which will curb the stream of visits to the house with the new arrival. The parents-to-be will also have a more realistic idea of what they still need and what the guests can bring as gifts.
Where Should we Have the Stork Tea?
If the parents-to-be have strong preferences – follow their lead. If not, there are a few options to consider. Baby showers at home have a more personal atmosphere, but having it at a restaurant or coffee shop may be a special treat. Hosting it at a place other than home means the hostess has less work, but may make the budget more complicated and limit the number of guests. A small and intimate baby shower with only a couple of friends may even work well in the form of a day-at-the-spa with the expecting mom
Hosting a baby shower involves numerous decisions. In all, it is best to put the preferences of the parents-to-be first. Try to be creative in decision making and give the parents-to-be a stork tea that they will fondly remember.
Butterflies by planting a Buddleia Bush or by letting the nettles grow? Government encourages gardeners and farmers to conserve butterfly habitats.
Is Britain entering a post-butterfly era? This fear has been expressed by Sir David Attenborough, much respected naturalist and TV broadcaster who for 50 years has been bringing the natural world into UK living rooms.
Survival Zones will be Grant Aided
He has thrown his weight behind a campaign to rescue native butterfly species from extinction. During an interview on BBC TV he announced 20 “Survival Zones” where farmers and growers will be eligible to apply for grant aid in order to create conservation areas by restoring habitat that has been destroyed for agriculture.
Butterflies under threat include the high brown fritillary and marsh fritillary that are found on Dartmoor, the Adonis Blue that is found on the Downs of southern England and the Swallow Tail that lives in the shrinking fenlands of the Norfolk Broads area.
Butterflies Are a Rarity in British Countryside
Sir David commented “Much of Britain’s countryside is a no-go area for many favourite butterflies. Habitat has been ploughed up or become overgrown. Anybody who’s been for a country walk recently will tell you that butterflies are a rarity.
The importance of butterflies is that they tell us if the land is healthy or not. If there is an absence of butterflies it means the land is endangered or sick.”
Restoring the Balance in Favour of Butterflies
The government has agreed to finance this initiative through grants to farmers, enabling them to restore land to provide the correct habitat for endangered species. Hopefully this will reverse the trend towards extinction.
How Can Individuals Help to Conserve Butterflies?
Individuals can do a lot to help save the butterfly. One simple initiative is to provide food and host plants for the butterfly population. A food plant provides nectar for the adult butterfly and so blossoms are important.
The butterfly then needs to lay its eggs on the leaves of a host plant such as the humble nettle (Urtica). After hatching the caterpillars will feed on the leaves of the host plant which also provides shelter for the chrysalis stage.
Some Butterfly Friendly Plants Include:
- The Buddleia Bush
- Honeysuckle – a fragrant climber that can be trained up a post or drainpipe
- Hebe (common name Veronica)
- Echinacea purpurea – common name Purple Coneflower
- Herbs such as Sage and Marjoram
- Monarda (common name Bee Balm)
or if you don’t have the time or energy for horticulture why not just allow a clump of nettles to grow in a corner of the garden.
A few more Do’s and Don’ts